The additional yield of a periodic screening programme for open-angle glaucoma: a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening (2024)

Abstract

Aim: To study the additional yield of a periodic screening programme for open-angle glaucoma (OAG) by comparing, in a population-based setting, incident OAG (iOAG) cases detected in regular ophthalmic care with those detected during screening.

Methods: Participants aged 55 and over from the population-based Rotterdam Study underwent the same ophthalmic examination at baseline (1991-3) and follow-up (1997-9), including visual field testing and simultaneous stereo optic disc photography. Of 3842 participants, 87 (2.3%) developed iOAG during a mean follow-up time of 6.5 years. Of these 87 iOAG cases, 78 (90%) were included in this study.

Results: Of the 78 iOAG cases detected at follow-up, 23 (29%) had already been detected before during regular ophthalmic care. The remaining 55 (71%) undetected iOAG cases more often showed glaucomatous optic neuropathy without glaucomatous visual field loss ( 29 of 55 (53%)) as compared with the detected cases ( four of 23 (17%); p = 0.009). Of the undetected iOAG cases, only four had developed significant visual field loss in their better eye.

Conclusion: The additional yield of a periodic OAG screening programme is lower than expected from published prevalence data. In the discussion, the authors estimate that - in a white population with a low prevalence of pseudoexfoliation - about one in 1000 screened persons could be saved from bilateral end-stage OAG.

Original languageEnglish
Pages (from-to)1222-1226
Number of pages5
JournalBRITISH JOURNAL OF OPHTHALMOLOGY
Volume92
Issue number9
DOIs
Publication statusPublished - Sept-2008

Keywords

  • BALTIMORE EYE SURVEY
  • BLUE-MOUNTAINS-EYE
  • VISUAL-FIELD TEST
  • INTRAOCULAR-PRESSURE
  • FAMILY HISTORY
  • RISK
  • ROTTERDAM
  • PROGRESSION
  • PREVALENCE
  • SUSPECTS

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Stoutenbeek, R., de Voogd, S., Wolfs, R. C. W., Hofman, A., de Jong, P. T. V. M. (2008). The additional yield of a periodic screening programme for open-angle glaucoma: a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening. BRITISH JOURNAL OF OPHTHALMOLOGY, 92(9), 1222-1226. https://doi.org/10.1136/bjo.2007.129130

Stoutenbeek, R. ; de Voogd, S. ; Wolfs, R. C. W. et al. / The additional yield of a periodic screening programme for open-angle glaucoma : a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening. In: BRITISH JOURNAL OF OPHTHALMOLOGY. 2008 ; Vol. 92, No. 9. pp. 1222-1226.

@article{1df634538cbd42029b959032bd60a374,

title = "The additional yield of a periodic screening programme for open-angle glaucoma: a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening",

abstract = "Aim: To study the additional yield of a periodic screening programme for open-angle glaucoma (OAG) by comparing, in a population-based setting, incident OAG (iOAG) cases detected in regular ophthalmic care with those detected during screening.Methods: Participants aged 55 and over from the population-based Rotterdam Study underwent the same ophthalmic examination at baseline (1991-3) and follow-up (1997-9), including visual field testing and simultaneous stereo optic disc photography. Of 3842 participants, 87 (2.3%) developed iOAG during a mean follow-up time of 6.5 years. Of these 87 iOAG cases, 78 (90%) were included in this study.Results: Of the 78 iOAG cases detected at follow-up, 23 (29%) had already been detected before during regular ophthalmic care. The remaining 55 (71%) undetected iOAG cases more often showed glaucomatous optic neuropathy without glaucomatous visual field loss ( 29 of 55 (53%)) as compared with the detected cases ( four of 23 (17%); p = 0.009). Of the undetected iOAG cases, only four had developed significant visual field loss in their better eye.Conclusion: The additional yield of a periodic OAG screening programme is lower than expected from published prevalence data. In the discussion, the authors estimate that - in a white population with a low prevalence of pseudoexfoliation - about one in 1000 screened persons could be saved from bilateral end-stage OAG.",

keywords = "BALTIMORE EYE SURVEY, BLUE-MOUNTAINS-EYE, VISUAL-FIELD TEST, INTRAOCULAR-PRESSURE, FAMILY HISTORY, RISK, ROTTERDAM, PROGRESSION, PREVALENCE, SUSPECTS",

author = "R. Stoutenbeek and {de Voogd}, S. and Wolfs, {R. C. W.} and A. Hofman and {de Jong}, {P. T. V. M.} and Jansonius, {N. M.}",

year = "2008",

month = sep,

doi = "10.1136/bjo.2007.129130",

language = "English",

volume = "92",

pages = "1222--1226",

journal = "BRITISH JOURNAL OF OPHTHALMOLOGY",

issn = "0007-1161",

publisher = "BMJ Publishing Group",

number = "9",

}

Stoutenbeek, R, de Voogd, S, Wolfs, RCW, Hofman, A, de Jong, PTVM 2008, 'The additional yield of a periodic screening programme for open-angle glaucoma: a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening', BRITISH JOURNAL OF OPHTHALMOLOGY, vol. 92, no. 9, pp. 1222-1226. https://doi.org/10.1136/bjo.2007.129130

The additional yield of a periodic screening programme for open-angle glaucoma: a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening. / Stoutenbeek, R.; de Voogd, S.; Wolfs, R. C. W. et al.
In: BRITISH JOURNAL OF OPHTHALMOLOGY, Vol. 92, No. 9, 09.2008, p. 1222-1226.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - The additional yield of a periodic screening programme for open-angle glaucoma

T2 - a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening

AU - Stoutenbeek, R.

AU - de Voogd, S.

AU - Wolfs, R. C. W.

AU - Hofman, A.

AU - de Jong, P. T. V. M.

AU - Jansonius, N. M.

PY - 2008/9

Y1 - 2008/9

N2 - Aim: To study the additional yield of a periodic screening programme for open-angle glaucoma (OAG) by comparing, in a population-based setting, incident OAG (iOAG) cases detected in regular ophthalmic care with those detected during screening.Methods: Participants aged 55 and over from the population-based Rotterdam Study underwent the same ophthalmic examination at baseline (1991-3) and follow-up (1997-9), including visual field testing and simultaneous stereo optic disc photography. Of 3842 participants, 87 (2.3%) developed iOAG during a mean follow-up time of 6.5 years. Of these 87 iOAG cases, 78 (90%) were included in this study.Results: Of the 78 iOAG cases detected at follow-up, 23 (29%) had already been detected before during regular ophthalmic care. The remaining 55 (71%) undetected iOAG cases more often showed glaucomatous optic neuropathy without glaucomatous visual field loss ( 29 of 55 (53%)) as compared with the detected cases ( four of 23 (17%); p = 0.009). Of the undetected iOAG cases, only four had developed significant visual field loss in their better eye.Conclusion: The additional yield of a periodic OAG screening programme is lower than expected from published prevalence data. In the discussion, the authors estimate that - in a white population with a low prevalence of pseudoexfoliation - about one in 1000 screened persons could be saved from bilateral end-stage OAG.

AB - Aim: To study the additional yield of a periodic screening programme for open-angle glaucoma (OAG) by comparing, in a population-based setting, incident OAG (iOAG) cases detected in regular ophthalmic care with those detected during screening.Methods: Participants aged 55 and over from the population-based Rotterdam Study underwent the same ophthalmic examination at baseline (1991-3) and follow-up (1997-9), including visual field testing and simultaneous stereo optic disc photography. Of 3842 participants, 87 (2.3%) developed iOAG during a mean follow-up time of 6.5 years. Of these 87 iOAG cases, 78 (90%) were included in this study.Results: Of the 78 iOAG cases detected at follow-up, 23 (29%) had already been detected before during regular ophthalmic care. The remaining 55 (71%) undetected iOAG cases more often showed glaucomatous optic neuropathy without glaucomatous visual field loss ( 29 of 55 (53%)) as compared with the detected cases ( four of 23 (17%); p = 0.009). Of the undetected iOAG cases, only four had developed significant visual field loss in their better eye.Conclusion: The additional yield of a periodic OAG screening programme is lower than expected from published prevalence data. In the discussion, the authors estimate that - in a white population with a low prevalence of pseudoexfoliation - about one in 1000 screened persons could be saved from bilateral end-stage OAG.

KW - BALTIMORE EYE SURVEY

KW - BLUE-MOUNTAINS-EYE

KW - VISUAL-FIELD TEST

KW - INTRAOCULAR-PRESSURE

KW - FAMILY HISTORY

KW - RISK

KW - ROTTERDAM

KW - PROGRESSION

KW - PREVALENCE

KW - SUSPECTS

U2 - 10.1136/bjo.2007.129130

DO - 10.1136/bjo.2007.129130

M3 - Article

SN - 0007-1161

VL - 92

SP - 1222

EP - 1226

JO - BRITISH JOURNAL OF OPHTHALMOLOGY

JF - BRITISH JOURNAL OF OPHTHALMOLOGY

IS - 9

ER -

Stoutenbeek R, de Voogd S, Wolfs RCW, Hofman A, de Jong PTVM, Jansonius NM. The additional yield of a periodic screening programme for open-angle glaucoma: a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening. BRITISH JOURNAL OF OPHTHALMOLOGY. 2008 Sept;92(9):1222-1226. doi: 10.1136/bjo.2007.129130

The additional yield of a periodic screening programme for open-angle glaucoma: a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening (2024)

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