Abstract
Aim: To study the additional yield of a periodic screening programme for open-angle glaucoma (OAG) by comparing, in a population-based setting, incident OAG (iOAG) cases detected in regular ophthalmic care with those detected during screening.
Methods: Participants aged 55 and over from the population-based Rotterdam Study underwent the same ophthalmic examination at baseline (1991-3) and follow-up (1997-9), including visual field testing and simultaneous stereo optic disc photography. Of 3842 participants, 87 (2.3%) developed iOAG during a mean follow-up time of 6.5 years. Of these 87 iOAG cases, 78 (90%) were included in this study.
Results: Of the 78 iOAG cases detected at follow-up, 23 (29%) had already been detected before during regular ophthalmic care. The remaining 55 (71%) undetected iOAG cases more often showed glaucomatous optic neuropathy without glaucomatous visual field loss ( 29 of 55 (53%)) as compared with the detected cases ( four of 23 (17%); p = 0.009). Of the undetected iOAG cases, only four had developed significant visual field loss in their better eye.
Conclusion: The additional yield of a periodic OAG screening programme is lower than expected from published prevalence data. In the discussion, the authors estimate that - in a white population with a low prevalence of pseudoexfoliation - about one in 1000 screened persons could be saved from bilateral end-stage OAG.
Original language | English |
---|---|
Pages (from-to) | 1222-1226 |
Number of pages | 5 |
Journal | BRITISH JOURNAL OF OPHTHALMOLOGY |
Volume | 92 |
Issue number | 9 |
DOIs | |
Publication status | Published - Sept-2008 |
Keywords
- BALTIMORE EYE SURVEY
- BLUE-MOUNTAINS-EYE
- VISUAL-FIELD TEST
- INTRAOCULAR-PRESSURE
- FAMILY HISTORY
- RISK
- ROTTERDAM
- PROGRESSION
- PREVALENCE
- SUSPECTS
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Stoutenbeek, R., de Voogd, S., Wolfs, R. C. W., Hofman, A., de Jong, P. T. V. M. (2008). The additional yield of a periodic screening programme for open-angle glaucoma: a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening. BRITISH JOURNAL OF OPHTHALMOLOGY, 92(9), 1222-1226. https://doi.org/10.1136/bjo.2007.129130
Stoutenbeek, R. ; de Voogd, S. ; Wolfs, R. C. W. et al. / The additional yield of a periodic screening programme for open-angle glaucoma : a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening. In: BRITISH JOURNAL OF OPHTHALMOLOGY. 2008 ; Vol. 92, No. 9. pp. 1222-1226.
@article{1df634538cbd42029b959032bd60a374,
title = "The additional yield of a periodic screening programme for open-angle glaucoma: a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening",
abstract = "Aim: To study the additional yield of a periodic screening programme for open-angle glaucoma (OAG) by comparing, in a population-based setting, incident OAG (iOAG) cases detected in regular ophthalmic care with those detected during screening.Methods: Participants aged 55 and over from the population-based Rotterdam Study underwent the same ophthalmic examination at baseline (1991-3) and follow-up (1997-9), including visual field testing and simultaneous stereo optic disc photography. Of 3842 participants, 87 (2.3%) developed iOAG during a mean follow-up time of 6.5 years. Of these 87 iOAG cases, 78 (90%) were included in this study.Results: Of the 78 iOAG cases detected at follow-up, 23 (29%) had already been detected before during regular ophthalmic care. The remaining 55 (71%) undetected iOAG cases more often showed glaucomatous optic neuropathy without glaucomatous visual field loss ( 29 of 55 (53%)) as compared with the detected cases ( four of 23 (17%); p = 0.009). Of the undetected iOAG cases, only four had developed significant visual field loss in their better eye.Conclusion: The additional yield of a periodic OAG screening programme is lower than expected from published prevalence data. In the discussion, the authors estimate that - in a white population with a low prevalence of pseudoexfoliation - about one in 1000 screened persons could be saved from bilateral end-stage OAG.",
keywords = "BALTIMORE EYE SURVEY, BLUE-MOUNTAINS-EYE, VISUAL-FIELD TEST, INTRAOCULAR-PRESSURE, FAMILY HISTORY, RISK, ROTTERDAM, PROGRESSION, PREVALENCE, SUSPECTS",
author = "R. Stoutenbeek and {de Voogd}, S. and Wolfs, {R. C. W.} and A. Hofman and {de Jong}, {P. T. V. M.} and Jansonius, {N. M.}",
year = "2008",
month = sep,
doi = "10.1136/bjo.2007.129130",
language = "English",
volume = "92",
pages = "1222--1226",
journal = "BRITISH JOURNAL OF OPHTHALMOLOGY",
issn = "0007-1161",
publisher = "BMJ Publishing Group",
number = "9",
}
Stoutenbeek, R, de Voogd, S, Wolfs, RCW, Hofman, A, de Jong, PTVM 2008, 'The additional yield of a periodic screening programme for open-angle glaucoma: a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening', BRITISH JOURNAL OF OPHTHALMOLOGY, vol. 92, no. 9, pp. 1222-1226. https://doi.org/10.1136/bjo.2007.129130
The additional yield of a periodic screening programme for open-angle glaucoma: a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening. / Stoutenbeek, R.; de Voogd, S.; Wolfs, R. C. W. et al.
In: BRITISH JOURNAL OF OPHTHALMOLOGY, Vol. 92, No. 9, 09.2008, p. 1222-1226.
Research output: Contribution to journal › Article › Academic › peer-review
TY - JOUR
T1 - The additional yield of a periodic screening programme for open-angle glaucoma
T2 - a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening
AU - Stoutenbeek, R.
AU - de Voogd, S.
AU - Wolfs, R. C. W.
AU - Hofman, A.
AU - de Jong, P. T. V. M.
AU - Jansonius, N. M.
PY - 2008/9
Y1 - 2008/9
N2 - Aim: To study the additional yield of a periodic screening programme for open-angle glaucoma (OAG) by comparing, in a population-based setting, incident OAG (iOAG) cases detected in regular ophthalmic care with those detected during screening.Methods: Participants aged 55 and over from the population-based Rotterdam Study underwent the same ophthalmic examination at baseline (1991-3) and follow-up (1997-9), including visual field testing and simultaneous stereo optic disc photography. Of 3842 participants, 87 (2.3%) developed iOAG during a mean follow-up time of 6.5 years. Of these 87 iOAG cases, 78 (90%) were included in this study.Results: Of the 78 iOAG cases detected at follow-up, 23 (29%) had already been detected before during regular ophthalmic care. The remaining 55 (71%) undetected iOAG cases more often showed glaucomatous optic neuropathy without glaucomatous visual field loss ( 29 of 55 (53%)) as compared with the detected cases ( four of 23 (17%); p = 0.009). Of the undetected iOAG cases, only four had developed significant visual field loss in their better eye.Conclusion: The additional yield of a periodic OAG screening programme is lower than expected from published prevalence data. In the discussion, the authors estimate that - in a white population with a low prevalence of pseudoexfoliation - about one in 1000 screened persons could be saved from bilateral end-stage OAG.
AB - Aim: To study the additional yield of a periodic screening programme for open-angle glaucoma (OAG) by comparing, in a population-based setting, incident OAG (iOAG) cases detected in regular ophthalmic care with those detected during screening.Methods: Participants aged 55 and over from the population-based Rotterdam Study underwent the same ophthalmic examination at baseline (1991-3) and follow-up (1997-9), including visual field testing and simultaneous stereo optic disc photography. Of 3842 participants, 87 (2.3%) developed iOAG during a mean follow-up time of 6.5 years. Of these 87 iOAG cases, 78 (90%) were included in this study.Results: Of the 78 iOAG cases detected at follow-up, 23 (29%) had already been detected before during regular ophthalmic care. The remaining 55 (71%) undetected iOAG cases more often showed glaucomatous optic neuropathy without glaucomatous visual field loss ( 29 of 55 (53%)) as compared with the detected cases ( four of 23 (17%); p = 0.009). Of the undetected iOAG cases, only four had developed significant visual field loss in their better eye.Conclusion: The additional yield of a periodic OAG screening programme is lower than expected from published prevalence data. In the discussion, the authors estimate that - in a white population with a low prevalence of pseudoexfoliation - about one in 1000 screened persons could be saved from bilateral end-stage OAG.
KW - BALTIMORE EYE SURVEY
KW - BLUE-MOUNTAINS-EYE
KW - VISUAL-FIELD TEST
KW - INTRAOCULAR-PRESSURE
KW - FAMILY HISTORY
KW - RISK
KW - ROTTERDAM
KW - PROGRESSION
KW - PREVALENCE
KW - SUSPECTS
U2 - 10.1136/bjo.2007.129130
DO - 10.1136/bjo.2007.129130
M3 - Article
SN - 0007-1161
VL - 92
SP - 1222
EP - 1226
JO - BRITISH JOURNAL OF OPHTHALMOLOGY
JF - BRITISH JOURNAL OF OPHTHALMOLOGY
IS - 9
ER -
Stoutenbeek R, de Voogd S, Wolfs RCW, Hofman A, de Jong PTVM, Jansonius NM. The additional yield of a periodic screening programme for open-angle glaucoma: a population-based comparison of incident glaucoma cases detected in regular ophthalmic care with cases detected during screening. BRITISH JOURNAL OF OPHTHALMOLOGY. 2008 Sept;92(9):1222-1226. doi: 10.1136/bjo.2007.129130